Avaliação do perfil de sangue total como ferramenta no diagnóstico e rastreamento da covid-19. Um estudo transversal

Autores

  • Nicolle Godoy Moreira aLaboratório de Análises Clínicas - Centro Universitário FMABC – Santo André, Brazil
  • Thaciane Alkmim Bibo aLaboratório de Análises Clínicas - Centro Universitário FMABC – Santo André, Brazil
  • Ana Carolina Macedo Gaiatto aLaboratório de Análises Clínicas - Centro Universitário FMABC – Santo André, Brazil
  • Joyce Regina Santos Raimundo aLaboratório de Análises Clínicas - Centro Universitário FMABC – Santo André, Brazil
  • Jéssica Freitas Araújo Encinas aLaboratório de Análises Clínicas - Centro Universitário FMABC – Santo André, Brazil
  • Beatriz da Costa Aguiar Alves aLaboratório de Análises Clínicas - Centro Universitário FMABC – Santo André, Brazil
  • Thaís Moura Gascón aLaboratório de Análises Clínicas - Centro Universitário FMABC – Santo André, Brazil
  • Fernando Luiz Affonso Fonseca aLaboratório de Análises Clínicas - Centro Universitário FMABC – Santo André, Brazil
  • Glaucia Luciano da Veiga aLaboratório de Análises Clínicas - Centro Universitário FMABC – Santo André, Brazil

DOI:

https://doi.org/10.36311/jhgd.v34.15750

Palavras-chave:

perfil hematológico, indice hematimétrico, COVID-19, pandemia, triagem

Resumo

Introdução: a epidemia de COVID-19 teve início em dezembro de 2019 e a falta de recursos diagnósticos impactou os dados divulgados sobre o número de casos, resultando em variações nos casos relatados entre os países. Essa situação destaca a necessidade de um conhecimento mais profundo sobre a fisiopatologia do SARS-CoV-2, como o perfil sanguíneo e possíveis preditores.

Método: variáveis hematológicas foram estudadas em 200 pacientes diagnosticados com COVID-19, antes do início do período de vacinação. Analisamos os parâmetros do hemograma: eritrócitos, hemoglobina, hemoglobina corpuscular média (HCM), concentração média de hemoglobina corpuscular (CMHC), hematócrito, amplitude de distribuição dos glóbulos vermelhos (RDW), plaquetas, volume plaquetário médio (VPM), leucócitos, neutrófilos, linfócitos, relação neutrófilos/linfócitos e razão plaquetas/linfócitos (RPL), até 9 dias após o resultado positivo para COVID-19.

Resultados: o grupo positivo para COVID-19 apresentou uma média de idade mais alta, assim como uma frequência maior de indivíduos do sexo masculino. Os valores de eritrócitos, hemoglobina, hematócrito e HCM foram significativamente menores, enquanto o RDW e o PRP apresentaram valores mais altos no grupo positivo. Os leucócitos, neutrófilos e a relação neutrófilos/linfócitos apresentaram valores mais altos no grupo positivo para COVID-19.

Conclusão: os dados mostraram que o hemograma, um exame de baixo custo e minimamente invasivo, apoia o diagnóstico e a triagem da COVID-19, permitindo uma melhor avaliação da evolução da doença e auxiliando nas decisões médicas diante da falta de recursos em uma situação de pandemia.

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2024-04-11

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ORIGINAL ARTICLES