Predictors of Mortality and Functional recovery after severe traumatic brain injury: protocol for a prospective cohort study

Autores/as

  • Jessica Vaz Gonçalves a Laboratório de Neurorreabilitação e Neuromodulação, Programa de Pós-graduação em Ciências Fisiológicas, Departamento de Ciências Fisiológicas, Universidade Federal do Espírito Santo, Vitória, Brasil;
  • Ramon da Silva Pereira a Laboratório de Neurorreabilitação e Neuromodulação, Programa de Pós-graduação em Ciências Fisiológicas, Departamento de Ciências Fisiológicas, Universidade Federal do Espírito Santo, Vitória, Brasil;
  • Rodrigo Miranda Groberio a Laboratório de Neurorreabilitação e Neuromodulação, Programa de Pós-graduação em Ciências Fisiológicas, Departamento de Ciências Fisiológicas, Universidade Federal do Espírito Santo, Vitória, Brasil;
  • Lucas Rodrigues Nascimento b Laboratório Caminhar, Programa de Pós-graduação em Ciências Fisiológicas, Departamento de Ciências Fisiológicas, Universidade Federal do Espírito Santo, Vitória, Brasil;
  • Walter Gomes da Silva a Laboratório de Neurorreabilitação e Neuromodulação, Programa de Pós-graduação em Ciências Fisiológicas, Departamento de Ciências Fisiológicas, Universidade Federal do Espírito Santo, Vitória, Brasil;
  • Hellen Siler Vasconcellos a Laboratório de Neurorreabilitação e Neuromodulação, Programa de Pós-graduação em Ciências Fisiológicas, Departamento de Ciências Fisiológicas, Universidade Federal do Espírito Santo, Vitória, Brasil;
  • Carla Bernardo Louzada a Laboratório de Neurorreabilitação e Neuromodulação, Programa de Pós-graduação em Ciências Fisiológicas, Departamento de Ciências Fisiológicas, Universidade Federal do Espírito Santo, Vitória, Brasil;
  • Larissa Cunha Silva Santos Ramos a Laboratório de Neurorreabilitação e Neuromodulação, Programa de Pós-graduação em Ciências Fisiológicas, Departamento de Ciências Fisiológicas, Universidade Federal do Espírito Santo, Vitória, Brasil;
  • Thais da Silva Rodrigues a Laboratório de Neurorreabilitação e Neuromodulação, Programa de Pós-graduação em Ciências Fisiológicas, Departamento de Ciências Fisiológicas, Universidade Federal do Espírito Santo, Vitória, Brasil;
  • Hanna Souza de Almeida a Laboratório de Neurorreabilitação e Neuromodulação, Programa de Pós-graduação em Ciências Fisiológicas, Departamento de Ciências Fisiológicas, Universidade Federal do Espírito Santo, Vitória, Brasil;
  • Fernando Zanela da Silva Arêas a Laboratório de Neurorreabilitação e Neuromodulação, Programa de Pós-graduação em Ciências Fisiológicas, Departamento de Ciências Fisiológicas, Universidade Federal do Espírito Santo, Vitória, Brasil; b Laboratório Caminhar, Programa de Pós-graduação em Ciências Fisiológicas, Departamento de Ciências Fisiológicas, Universidade Federal do Espírito Santo, Vitória, Brasil;

DOI:

https://doi.org/10.36311/jhgd.v33.14929

Palabras clave:

traumatic brain injury, mortality, Keywords: Resistance exercise, water aerobics, functionality and old age., predictors, protocol

Resumen

Introduction: traumatic brain injury is a global public health problem due to its severity and high rates of morbimortality worldwide. Identifying predictors associated with increased mortality and unfavorable functional outcomes after the traumatic brain injury event is crucial for minimizing morbidity and mortality rates. Therefore, this study aims to establish a protocol to investigate the predictors of mortality and functional recovery after severe traumatic brain injury in Brazil.

Methods: The study will include all patients admitted for severe traumatic brain injury (Glasgow Coma Scale ≤ 8) at the State Hospital of Urgency and Emergency, which is the referral trauma hospital of Espirito Santo. The outcomes of interest are hospital mortality and functional recovery 24 months after hospital discharge. Subjects will be followed up at seventy-two hours, three months, six months, twelve months, and twenty-four months after the trauma. Morbidity will be determined by assessing: 1) the level of motor and cognitive disability, 2) functional impairment and quality of life, and 3) aspects of rehabilitation treatment. Additionally, the traumatic brain injury load, estimated by the years of life lost, will be calculated.

Discussion: the results of this study will help identify variables that can predict morbidity and mortality, as well as diagnostic and therapeutic targets for patients with severe traumatic brain injury. Furthermore, the findings will have practical implications for: 1) the development of public policies, 2) investments in hospital infrastructure 3) understanding the socioeconomic impact of functional loss in the individuals.

Study registration: the study received approval from the Ethics Committee of the Federal University of Espirito Santo under protocol number 4.222.002 on August 18, 2020.

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Publicado

2023-08-14

Número

Vol. 33 Núm. 2 (2023)

Sección

ORIGINAL ARTICLES

Licencia

Derechos de autor 2023 Gonçalves JV, Pereira RS, Groberio RM, Nascimento LR, Silva WG, Vasconcellos HS, Louzada CB, Ramos LCSS, Rodrigues TS, Almeida HS, Arêas FZS

Creative Commons License

Esta obra está bajo una licencia internacional Creative Commons Atribución 4.0.