Quality of life and associated factors in patients with hematological cancer according to EORTC QLQ-C30

Authors

  • Mariana de Souza Vieira a Programa de Pós-graduação em Nutrição e Saúde, Universidade Federal do Espírito Santo, Avenida Marechal Campos, 1468 – Maruípe, Vitória, Espírito Santo, CEP: 29040-090, Brasil;
  • Lorraine Pires Avancini b Departamento Integrado de Educação e Saúde, Universidade Federal do Espírito Santo, Avenida Marechal Campos, 1468 – Maruípe, Vitória, Espírito Santo, CEP: 29040-090, Brasil;
  • Laís Freitas da Costa b Departamento Integrado de Educação e Saúde, Universidade Federal do Espírito Santo, Avenida Marechal Campos, 1468 – Maruípe, Vitória, Espírito Santo, CEP: 29040-090, Brasil;
  • Glenda Blaser Petarli c Hospital Universitário Cassiano Antonio Moraes, Vitória, ES 29043-260, Brasil;
  • Taísa Sabrina Silva Pereira d Universidad de las Américas Puebla, San Andrés Cholula, Puebla. C.P. 72810, México.
  • José Luiz Marques Rocha a Programa de Pós-graduação em Nutrição e Saúde, Universidade Federal do Espírito Santo, Avenida Marechal Campos, 1468 – Maruípe, Vitória, Espírito Santo, CEP: 29040-090, Brasil; b Departamento Integrado de Educação e Saúde, Universidade Federal do Espírito Santo, Avenida Marechal Campos, 1468 – Maruípe, Vitória, Espírito Santo, CEP: 29040-090, Brasil;
  • Valdete Regina Guandalini a Programa de Pós-graduação em Nutrição e Saúde, Universidade Federal do Espírito Santo, Avenida Marechal Campos, 1468 – Maruípe, Vitória, Espírito Santo, CEP: 29040-090, Brasil; b Departamento Integrado de Educação e Saúde, Universidade Federal do Espírito Santo, Avenida Marechal Campos, 1468 – Maruípe, Vitória, Espírito Santo, CEP: 29040-090, Brasil;

DOI:

https://doi.org/10.36311/jhgd.v32.12788

Keywords:

Malnutrition, Cancer, Nutritional Assessment, Functional Performance, Cognition

Abstract

Introduction: Hematological cancers account for 9% of all cancers and their progression and treatment directly affect quality of life (QoL).

Objective: This study assessed QoL and associated factors in patients with hematological cancer according to the EORTC QLQ-C30.

Methods: Cross-sectional study carried out from August 2017 to June 2019. We included adults and the elderly of both sexes, with hematological cancer, undergoing oral or venous chemotherapy. Nutritional status was assessed by the Patient-Generated Subjective Global Assessment (PG-SGA) and QoL by EORTC QLQ-C30.

Results: Fifty-one patients aged in average 60.0 ± 15 years were evaluated. Of these, 51.0% were women, 80.4% were non-white, 37.3% had B lymphoid cell neoplasia, 60.8% had been diagnosed for ≤ 3 years, 77.1% were on chemotherapy, and 64.7% were well- nourished. The scores for global health status and functional scales were high and for symptoms and single items they were low, indicating good QoL and functionality and low symptomatology. After multivariate linear regression, the time of diagnosis ≤ 3 years was associated with functional performance (p <0.05) and malnutrition was associated with cognitive function (p <0.05) and with symptoms of fatigue, nausea and vomiting, and insomnia (p <0.05).

Conclusions: The patients evaluated had good quality of life and functionality, few symptoms, and were well-nourished. Time of diagnosis and malnutrition were associated with the role functioning and cognitive functioning domains, and with symptoms, fatigue, nausea and vomiting, and insomnia.

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Published

2022-10-31

Issue

Vol. 32 No. 3 (2022)

Section

ORIGINAL ARTICLES

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