Relationship between quality of life and sociodemographic, clinical and lifestyle characteristics of patients undergoing hemodialysis

Authors

  • Marina Abelha Barreto Postgraduate program in nutrition and health, Health Science Center, Federal University of Espírito Santo (UFES), Vitória, Espírito Santo, Brasil.
  • Monica Cattafesta Postgraduate program in Public health, Health Science Center, University, Federal University of Espírito Santo (UFES), Vitória, Espírito Santo, Brasil.
  • Alexandre Cardoso da Cunha Department of occupational therapy, Health Science Center, University, Federal University of Espírito Santo (UFES), Vitória, Espírito Santo, Brasil.
  • Mirian Patricia Castro Pereira Paixão Salesiano University Center, Vitória, Espírito Santo, Brasil
  • Edson Theodoro dos Santos Neto Department of public health, Health Science Center, Federal University of Espírito Santo (UFES), Vitória, Espírito Santo, Brasil.
  • Luciane Bresciani Salaroli Postgraduate program in nutrition and health, Health Science Center, Federal University of Espírito Santo (UFES), Vitória, Espírito Santo, Brasil; Department of public health, Health Science Center, Federal University of Espírito Santo (UFES), Vitória, Espírito Santo, Brasil.

DOI:

https://doi.org/10.36311/jhgd.v33.15422

Abstract

Introduction: In chronic diseases, QoL depends on several factors such as the type and duration of the disease, its treatment and side effects, the severity of symptoms, medication effects, patient age, limitations and self-care capacity. In chronic kidney disease it has also become a measure of health outcome.
Objective: assess the association between QoL and socioeconomic, lifestyle and clinical factors of patients on HD.
Methods: This is a cross-sectional epidemiological census, carried out among 1,024 patients on hemodialysis from all hemodialysis units at the metropolitan region in the Espirito Santo’s, Brazil . Sociodemographic, lifestyle and clinical characteristics data were used. QoL was assessed using the Short-Form health Survey-36 (SF-36). Data were analysed by multiple linear regression.
Results: The best QoL was represented by mental health (72.16) and the worst QoL by the physical aspect (26.78). After multiple linear regression, predictors of QoL were identified, with emphasis on males, a predictor of better QoL for 5 of the 8 domains and the summaries of the physical and mental components. Education, associated with 5 domains, gives greater reference to income. Physical activity was a predictor of 7 of the 8 QoL domains and the summary of the physical component. Among the clinical variables, the number of complications is associated with 7 of the 8 domains and summaries of the physical and mental components.
Conclusion: Male sex is highlighted as a predictor of better physical and mental health and elderly people with better mental health, despite the impairment in physical health. The absence of physical activity is associated with worse physical and mental health. Clinically, having 3 or more intradialytic complications was associated with worse physical and mental QoL.

Downloads

Download data is not yet available.

References

World Health Organization. Global status report on noncommunicable diseases 2010. World Health Organization. 2011. Accessed in february 15. https://apps.who.int/iris/handle/10665/44579.

GBD Chronic Kidney Disease Collaboration. Global, regional, and national burden of chronic kidney disease, 1990-2017: a systematic analysis for the Global Burden of Disease Study 2017. Lancet (London, England). 2020; 395(10225), 709–733. https://doi.org/10.1016/S0140-6736(20)30045-3

Thomé FS, Sesso RC, Lopes AA, Lugon JR, Martins CT. Inquérito Brasileiro de Diálise Crônica 2017. Braz J Nephrol. 2019;41 (2): 208-14. https://doi.org/10.1590/2175-8239-JBN-2018-0178

Neves PD, Sesso RC, Thomé RS, Lugon JR, Nascimento MM. Censo Brasileiro de Diálise: análise de dados da década 2009-2018. Braz J Nephrol. 2020;42(2):191-200. https://doi.org/10.1590/2175-8239-JBN-2019-0234

Sousa-Martins PD, Moura A, Madureira J, Alija P, Oliveira JG, Lopez M, Filgueiras M, Amado L, Sameiro-Faria M, Miranda V, Mesquita E, Teixeira L, Poveda V, Lobato L, Santos-Silva A, Costa E. Risk factors for mortality in end-stage kidney disease patients under online-hemodiafiltration: three-year follow-up study. Biomarkers. 2016;21 (6): 544-50. https://doi.org/10.3109/1354750X.2016.1160428

Ayanda KA, Abiodum OA, Ajiboye PO. Quality of Life of Chronic Kidney Disease Patients in a Nigerian Teaching Hospital. JBAH. 2014;4(5):17–28. https://iiste.org/Journals/index.php/JBAH/article/view/11229/11519

Brito DCS, Machado EL, Reis IA, Moreira DP, Nébias THM, Cherchiglia ML. Modality transition on renal replacement therapy and quality of life of patients: a 10-year follow-up cohort study. Qual Life Res. 2019;28(6):1485-1495. https://doi.org/10.1007/s11136-019-02113-z

Legrand K, Speyer E, Stengel B, Frimat, L, Ngueyon Sime W, Massy ZA, Fouque D, Laville M, Combe C, Jacquelinet C, Durand AC, EdetS, Gentile S, Briançon S, Ayav C. Perceived Health and Quality of Life in Patients With CKD, Including Those With Kidney Failure: Findings From National Surveys in France. Am J Kidney Dis. 2020;75(6):868-878. https://doi.org/10.1053/j.ajkd.2019.08.026

Zyga S, Alikari V, Sachlas A, Stathoulis, J, Aroni A, Theofilou P, Panoutsopoulos G. Management of Pain and Quality of Life in Patients with Chronic Kidney Disease Undergoing Hemodialysis. Pain Manag Nurs. 2015;16(5), 712–720. https://doi.org/10.1016/j.pmn.2015.03.004

Seidl EM, Zannon CML. Qualidade de vida e saúde: aspectos conceituais e metodológicos. Cad Saúde Pública. 2004;20(2), 580-8. https://doi.org/10.1590/S0102-311X2004000200027

Awuah KT, Finkelstein SH, Finkelstein FO. Quality of life of chronic kidney disease patients in developing countries. Kidney Int Suppl. 2013;3(2), 227–229. https://doi.org/10.1038/kisup.2013.20

Broers JHN, Kooman LA, van der Sande FM, Lacson E, Jr Kotanko P, Maddux FW. Quality of Life in Dialysis Patients: A Retrospective Cohort Study. Nephron. 2015;130(2):105-12. https://doi.org/10.1159/000430814

Cruz MC, Andrade C, Urrutia M, Draibe S, Nogueira-Martins LA, Sesso RC. Quality of life in patients with chronic kidney disease. Clinics. 2011;66(6):991-995. https://doi.org/10.1590/s1807-59322011000600012

Barreto SM, Ladeira RM, Duncan BB, Schmidt MI, Lopes AA, Benseñor IM, Chor D, Griep RH, Vidigal PG, Ribeiro AL, Lotufo PA, Mill JG. Chronic kidney disease among adult participants of the ELSA-Brasil cohort: association with race and socioeconomic position. J Epidemiol and Community Health. 2015;70:380–389. https://doi.org/10.1136/jech-2015-205834

Jha V, Garcia-Garcia G, Iseki K, Li Z, Naicker S, Plattner B, Saran R, Wang AY, Yang CW. Chronic kidney disease: global dimensions and perspectives. Lancet. 2013;20;382(9888):260-72. https://doi.org/10.1016/S0140-6736(13)60687-X

Moreira CA, Junior WG, lima LF, Lima RC, Ribeiro JF, Miranda AF . Avaliação das propriedades psicométricas básicas para a versão em português do KDQOL-SFTM. Rev Assoc Med Bras. 2009;55(1): 22-8. https://doi.org/10.1590/S0104-42302009000100010

Kefale B, Alebachew M, Tadesse Y, Engidawork E. Quality of life and its predictors among patients with chronic kidney disease: A hospital-based cross sectional study. PloS one. 2019;14(2), e0212184. https://doi.org/10.1371/journal.pone.0212184

Han SS, Kim KW, Na KY, Chae DW, Kim YS, Kim S, Chin HJ. Quality of life and mortality from a nephrologist’s view: a prospective observational study. BMC nephrology. 2009;10, 39. https://doi.org/10.1186/1471-2369-10-39

Kalantar-zazeh K, Kople JD, Block G, Humphreys MH. Association among SF36 quality of life measures and nutrition, hospitalization, and mortality in hemodialysis. J Am Soc Nephrol, 2001;12(12):2797-2806. https://doi.org/10.1681/ASN.V12122797

Ibrahim N, Teo SS, Che Din N, Abdul Gafor AH, Ismail R. The Role of Personality and Social Support in Health-Related Quality of Life in Chronic Kidney Disease Patients. PloS one. 2015;10(7), e0129015. https://doi.org/10.1371/journal.pone.0129015

Han, E., Shiraz, F., Haldane, V. et al. Biopsychosocial experiences and coping strategies of elderly ESRD patients: a qualitative study to inform the development of more holistic and person-centred health services in Singapore. BMC Public Health 19, 1107 (2019). https://doi.org/10.1186/s12889-019-7433-6

Jeremias-Martins E, Chatkin JM. Does everyone who quit smoking gain weight? A real-world prospective cohort study. J Bras Pneumol. 2019;45(1):e20180010. http://dx.doi.org/10.1590/1806-3713/e20180010

WHO guidelines on physical activity and sedentary behaviour. Geneva: World Health Organization; 2020. https://www.who.int/publications/i/item/9789240015128

Ciconelli R, Ferraz M, Santos W, Meinão I, Quaresma MR. Tradução para a língua portuguesa e validação do questionário genérico de avaliação de qualidade de vida SF-36 (Brasil SF-36). Rev Bras Reumatol, 1999;39(3):143-50. https://www.ufjf.br/renato_nunes/files/2014/03/Valida%25C3%25A7%25C3%25A3o-do-Question%25C3%25A1rio-de-qualidade-de-Vida-SF-36.pdf

Ware JE, Sherbourne CD. The MOS 36-item short-form health survey (SF-36). I. Conceptual framework and item selection. Med Care. 1992;30(6), 473–483. https://pubmed.ncbi.nlm.nih.gov/1593914/

Oliveira TS, Valente AT, Caetano CG, Garagarza CA. Nutritional parameters as mortality predictors in hemodialysis: differences between genders. Journal of Renal Care. 2017;43(2):83-91. https://doi.org/10.1111/jorc.12201

Bohlke M, Nunes DL, Marini SS, Kitamura C, Andrade M, Von-Gysel MP. Predictors of quality of life among patients on dialysis in southern Brazil. Sao Paulo Med J. 2008;126(5):252-6. https://doi.org/10.1590/S1516-31802008000500002

Machado LR, Car MR. A dialética da vida cotidiana de doentes com insuficiência renal crônica: entre o inevitável e o casual. Rev Esc Enferm USP. 2003;37(3): 27-35v. https://doi.org/10.1590/S0080-62342003000300004

Zhou X, Xue F, Wang H, Li L, Li R. The quality of life and associated factors in patients on maintenance hemodialysis - a multicenter study in Shanxi province. Ren Fail. 2017;39(1),707–711. https://doi.org/10.1080/0886022X.2017.1398095

Hall RK, Cary MPJ, Washington TR, Cólon-Emeric CS. Quality of life in older adults receiving hemodialysis: a qualitative study. Qual Life Res. 2020;29(3):655-663. https://doi.org/10.1007/s11136-019-02349-9

Fukushima RL, Costa JL, Orlandi FS. Atividade física e qualidade de vida de pacientes com doença renal crônica em hemodiálise. Fioter Pesqui. 2018;25(3):338-344. https://doi.org/10.1590/1809-2950/18021425032018

Pan CW, Wu Y, Zhou HJ, Xu BX, Wang P. Health-Related Quality of Life and Its Factors of Hemodialysis Patients in Suzhou, China. Blood Purif. 2018;45(4): 327-333. https://doi.org/10.1159/000485962

Gerogianni G, Lianos E, Kouzoupis A, Polikandrioti M, Grapsa E. The role of socio-demographic factors in depression and anxiety of patients on hemodialysis: an observational cross-sectional study. Int Urol Nephrol. 2018;50(1):143-154. https://doi.org/10.1007/s11255-017-1738-0

Norris KC, Williams SF, Rhee CM, Nicholas SB, Kovesdy CP, Kalantar-Zadeh K, Ebony Boulware L. Hemodialysis Disparities in African Americans: The Deeply Integrated Concept of Race in the Social Fabric of Our Society. Semin Dial. 2017;30(3), 213–223. https://doi.org/10.1111/sdi.12589

Wilkinson E, Brettle A, Waqar M, Randhawa G. Inequalities and outcomes: end stage kidney disease in ethnic minorities. BMC Nephrol. 2019;20(1):234. https://doi.org/10.1186/s12882-019-1410-2

Eneanya ND, Maddux DW, Reviriego-Mendoza MM, Larkin JW, Usvyat LA, van der Sande FM, Kooman JP, Maddux FW. Longitudinal patterns of health-related quality of life and dialysis modality: a national cohort study. BMC Nephrol. 2019;20, 7. https://doi.org/10.1186/s12882-018-1198-5

Lopes GB, James SA, Lopes MB, Penalva CC, Silva CTJE, Matos CM, Martins MTS, Lopes AA. John Henryism and Perceived Health among Hemodialysis Patients in a Multiracial Brazilian Population: the PROHEMO. Ethn Dis. 2018;28(4), 539–548. https://doi.org/10.18865/ed.28.4.539

Zyoud SH, Daraghmeh DN, Mezyed DO, Khdeir R, Sawafta MN, Ayaseh NA, Tabeeb GH, Sweileh WM, Awang R, Al-Jabi SW. Factors affecting quality of life in patients on haemodialysis: a cross-sectional study from Palestine. BMC Nephrol. 2016;17(1), 44. https://doi.org/10.1186/s12882-016-0257-z

Hornik B, Duława J. Frailty, Quality of Life, Anxiety, and Other Factors Affecting Adherence to Physical Activity Recommendations by Hemodialysis Patients. Int J Environ Res Public Health. 2019;16(10), 1827. https://doi.org/10.3390/ijerph16101827

Ramos ECC, Santos IS, Zanini RV, Ramos JMG. Qualidade de vida de pacientes renais crônicos em diálise peritoneal e hemodiálise. J Bras Nefrol. 2015;37(3):297-305. http://doi:10.5935/0101-2800.20150049

K/DOQI Workgroup. K/DOQI clinical practice guidelines for cardiovascular disease in dialysis patients. Am J Kidney Dis. 2005;45(4 Suppl 3):S1-153. https://doi.org/10.1053/j.ajkd.2005.01.019

Mallamaci F, Pisano A, Tripepi G. Physical activity in chronic kidney disease and the EXerCise Introduction To Enhance trial. Nephrol Dial Transplant. 2020;35(Suppl 2), ii18–ii22. https://doi.org/10.1093/ndt/gfaa012

Manfredini F, Mallamaci F, D’Arrigo G, Baggetta R, Bolignano D, Torino C, Lamberti N, Bertoli S, Ciurlino D, Rocca-Rey L, Barillà A, Battaglia Y, Rapanà RM, Zuccalà A, Bonanno G, Fatuzzo P, Rapisarda F, Rastelli S, Fabrizi F, Messa P, … Zoccali C. Exercise in Patients on Dialysis: A Multicenter, Randomized Clinical Trial. J Am Soc Nephrol. 2017;28(4), 1259–1268. https://doi.org/10.1681/ASN.2016030378

Fitzpatrick J, Sozio SM, Jaar BG, Estrella MM, Segev DL, Parekh RS, McAdams-DeMarco MA. Frailty, body composition and the risk of mortality in incident hemodialysis patients: the Predictors of Arrhythmic and Cardiovascular Risk in End Stage Renal Disease study. Nephrol Dial Transplant. 2019;34(2), 346–354. https://doi.org/10.1093/ndt/gfy124

Johansen KL, Chertow GM, Ng AV, Mulligan K, Carey S, Schoenfeld PY, Kent-Braun JA. Physical activity levels in patients on hemodialysis and healthy sedentary controls. Kidney Int. 2000;57(6): 2564-70. https://doi.org/10.1046/j.1523-1755.2000.00116.x

Manfredini F, Lamberti N, Malagoni AN, Felisatti M, Zuccalà A, Torino C, Tripepi G, Catizone L, Mallamaci F, Zoccali C. The role of deconditioning in the end-stage renal disease myopathy: physical exercise improves altered resting muscle oxygen consumption. Am J Nephrol. 2015;41 (4-5): 329-36. https://doi.org/10.1159/000431339

Khatib ST, Hemadneh MK, Hasan SA, Khazneh E, Zyoud SH. Quality of life in hemodialysis diabetic patients: a multicenter cross-sectional study from Palestine. BMC Nephrol. 2018;19(1), 49. https://doi.org/10.1186/s12882-018-0849-x

Dejvorakul S, Kumar R, Srirojanakul S, Panupichit N, Somrongthong R. Factors predicted with quality of life among hemodialysis patients in private hospital of Thailand. Hosp Pract. 2019;47(5): 254-258. http://doi:10.1080 / 21548331.2019.1682879

Lee WC, Lee YT, Li LC, Ng HY, Kuo WH, Lin PT, Liao YC, Chiou TT, Lee CT. The Number of Comorbidities Predicts Renal Outcomes in Patients with Stage 3⁻5 Chronic Kidney Disease. J Clin Med. 2018;7(12),493. http://doi:10.3390/jcm7120493

Sullivan MK, Rankin AJ, Jani BD, Mair FS, Mark PB. Associations between multimorbidity and adverse clinical outcomes in patients with chronic kidney disease: a systematic review and meta-analysis. BMJ Open. 2020;10(6), e038401. http://doi:10.1136/bmjopen-2020-038401

Chiu YW, Teitelbaum I, Misra M, Leon EM, Adzize T, Mehrotra R. Pill burden, adherence, hyperphosphatemia, and quality of life in maintenance dialysis patients. Clin J Am Soc Nephrol. 2009;4(6), 1089–1096. http://doi:10.2215/CJN.00290109

Davenport A. Intradialytic complications during hemodialysis. Hemodialysis International. 2006;10 (2): 162-7. http://doi:10.1111 / j.1542-4758.2006.00088.x

Downloads

Published

2023-12-01

Issue

Section

ORIGINAL ARTICLES